Thyroid peroxidase antibody (TPO–Ab) is associated with increased risk of adverse pregnancy outcomes.  The present study was aimed to find out the prevalence of thyroid peroxidise antibodies (TPO–Ab) in the study population

 Methods: 

This cross sectional prevalence study was conducted on a total of 130 patients who had preterm deliveries, intra uterine deaths and miscarriages were included in the study for the period 8 months at a tertiary care hospital.

 

Results:

 

. The prevalence of high TPO–Ab in the study population was 5.4%. The proportion of High TPO Ab was seen in women with preterm births followed by miscarriages and IUD of the study population.  

 

Conclusions: 

 

  The association of TPOAb and TSH is strong and significant at p value is <0.000297 and it leads to developing hypothyroidism during pregnancy. The screening of TSH and TPOAb is essential during pregnancy to avoid complications related pregnancy.