Introduction: This observational study on two port laparoscopic cholecystectomy was done to evaluate the technique of the two port laparoscopic cholecystectomy and to analyse the feasibility and effectiveness of the same in a tertiary care set–up in India. Materials and Methods: In a total of thirty patients undergoing laparoscopic cholecystectomy for gallstone disease, two ports i.e., a 10mm umbilical port and a 5mm epigastric ports were used for the bimanual manipulation of the gallbladder. Outcomes were measured in terms of the operative time, requirement of drainage tubes, conversion to conventional four port cholecystectomy, post–operative pain scores, time for discharge and occurrence of early complications. Results: Out of 30 patients, the male: female ratio was 13:2 and the mean age 29.6 years. The mean operative time was 39.57 minutes, post–operative pain was significantly low upto 24 hours. With low analgesia requirements upto 2.03 doses in 24 hours, and return to daily activity by 3.67 days, with better patient satisfaction. Length of hospital stay was 1.27 days and the post–operative complications were nil in our study. Conclusion: Two port laparoscopic cholecystectomy resulted in decreased pain, analgesia requirements, better cosmesis & low operative times. Thus, it can be recommended in a tertiary care set–up in India in selected patients.