Aim: .To compare the efficacy of 0.1% Ropivacaine with Tramadol, Buprenorphine and Fentanyl for relief of low back pain and sciatica, its effect on vital parameters and any side effects.

Method: 90 patients belonging to ASA grade 1and 2 were allocated into 3 groups. Group A received Tramadol 50 mg, Group B received Buprenorphine 0.1mg and Group C fentanyl  20micrograms.The patient were observed pre block, then at  1hr,4 hr.(at discharge ) ,24hr then 1week and 6 weeks after block. The assessment of pain was done using Visual analogue scale. The data was tabulated and statistically analyzed using student paired “t– test”.

Result: In cases of sciatica results were excellent (71.42%) after 1 and 6 weeks, while in patient with PID it was 58.22%. In patient with sacral canal stenosis there was no relief in pain. In all the 3 groups of analgesics, pain relief was statistically and clinically significant after 1 hour of caudal epidural injection.

Conclusion: We concluded from the study that extradural medication through epidural route in the treatment of low back pain proved to be of great success in various etiological factors. It is one of the best non–surgical,semiinvasivemethodsavailable. The use of adjuvants like Tramadol, Buprenorphine and fentanyl increased the efficacy of analgesia.